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Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis

BACKGROUND: Previously, we showed that M3 muscarinic receptor (M3R; gene name Chrm3) deficiency attenuates murine intestinal neoplasia, supporting the hypothesis that muscarinic receptors play an important role in intestinal tumorigenesis. METHODS: To test this hypothesis, in the present study we tr...

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Detalhes bibliográficos
Main Authors: Peng, Zhongsheng, Heath, Jonathon, Drachenberg, Cinthia, Raufman, Jean-Pierre, Xie, Guofeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640951/
https://ncbi.nlm.nih.gov/pubmed/23617763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-204
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