Signaling Pathways Differentially Affect RNA Polymerase II Initiation, Pausing, and Elongation Rate in Cells

RNA polymerase II (Pol II) transcribes hundreds of kilobases of DNA, limiting the production of mRNAs and lncRNAs. We used Global Run-on Sequencing (GRO-seq) to measure the rates of transcription by Pol II following gene activation. Elongation rates vary as much as 4-fold at different genomic loci a...

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Detaylı Bibliyografya
Asıl Yazarlar: Danko, Charles G., Hah, Nasun, Luo, Xin, Martins, André L., Core, Leighton, Lis, John T., Siepel, Adam, Kraus, W. Lee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640649/
https://ncbi.nlm.nih.gov/pubmed/23523369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.015
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