A New Class of Small Molecule Inhibitor of BMP Signaling

Growth factor signaling pathways are tightly regulated by phosphorylation and include many important kinase targets of interest for drug discovery. Small molecule inhibitors of the bone morphogenetic protein (BMP) receptor kinase ALK2 (ACVR1) are needed urgently to treat the progressively debilitati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sanvitale, Caroline E., Kerr, Georgina, Chaikuad, Apirat, Ramel, Marie-Christine, Mohedas, Agustin H., Reichert, Sabine, Wang, You, Triffitt, James T., Cuny, Gregory D., Yu, Paul B., Hill, Caroline S., Bullock, Alex N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639963/
https://ncbi.nlm.nih.gov/pubmed/23646137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062721
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