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Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation

The detection and quantification of genetic heterogeneity in populations of cells is fundamentally important to diverse fields, ranging from microbial evolution to human cancer genetics. However, despite the cost and throughput advances associated with massively parallel sequencing, it remains chall...

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Bibliografski detalji
Glavni autori: Hiatt, Joseph B., Pritchard, Colin C., Salipante, Stephen J., O'Roak, Brian J., Shendure, Jay
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638140/
https://ncbi.nlm.nih.gov/pubmed/23382536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.147686.112
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