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Assaying chromosomal inversions by single molecule haplotyping
Inversions are an important form of structural variation, but are difficult to characterize as their breakpoints often fall within inverted repeats. We have developed a novel method, called ‘Haplotype Fusion’, in which an inversion breakpoint is genotyped by performing Fusion-PCR on single molecules...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2690135/ https://ncbi.nlm.nih.gov/pubmed/16721377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth881 |
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