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Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation
The detection and quantification of genetic heterogeneity in populations of cells is fundamentally important to diverse fields, ranging from microbial evolution to human cancer genetics. However, despite the cost and throughput advances associated with massively parallel sequencing, it remains chall...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638140/ https://ncbi.nlm.nih.gov/pubmed/23382536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.147686.112 |
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