A carregar...

Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma

Granule neuron precursors (GNPs) are the most actively proliferating cells in the post-natal nervous system and mutations in pathways controlling their cell cycle can result in medulloblastoma. The transcription factor Atoh1 has been suspected to contribute to GNP proliferation, but its role in norm...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Flora, Adriano, Klisch, Tiemo J., Schuster, Gabriele, Zoghbi, Huda Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638077/
https://ncbi.nlm.nih.gov/pubmed/19965762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1181453
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!