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Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth
Treatment for medulloblastoma, the most common malignant brain tumor in children, remains limited to surgical resection, radiation, and traditional chemotherapy; with long-term survival as low as 50–60% for Sonic Hedgehog (Shh)-type medulloblastoma. We have shown that the transcription factor Atonal...
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Publicado no: | eLife |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736349/ https://ncbi.nlm.nih.gov/pubmed/29168692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31181 |
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