ATOH1 promotes leptomeningeal dissemination and metastasis of Sonic Hedgehog subgroup medulloblastomas

Medulloblastoma (MB) arising from the cerebellum is the most common pediatric brain malignancy, with leptomeningeal metastases often present at diagnosis and recurrence associated with poor clinical outcome. In this study, we employed mouse MB models to explore the relationship of tumor pathophysiol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Grausam, Katie B., Dooyema, Samuel D. R., Bihannic, Laure, Premathilake, Hasitha, Morrissy, A. Sorana, Forget, Antoine, Schaefer, Amanda M., Gundelach, Justin H., Macura, Slobodan, Maher, Diane M., Wang, Kevin, Heglin, Alex H., Ge, Xijin, Zeng, Erliang, Puget, Stephanie, Chandrasekar, Indra, Surendran, Kameswaran, Bram, Richard J., Schüller, Ulrich, Talyor, Michael D., Ayrault, Olivier, Zhao, Haotian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512702/
https://ncbi.nlm.nih.gov/pubmed/28490517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1836
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