Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

While the induction of a neutralizing antibody response against HIV remains a daunting goal, data from both natural infection and vaccine-induced immune responses suggest that it may be possible to induce antibodies with enhanced Fc effector activity and improved antiviral control via vaccination. H...

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Autores principales: Ackerman, Margaret E., Crispin, Max, Yu, Xiaojie, Baruah, Kavitha, Boesch, Austin W., Harvey, David J., Dugast, Anne-Sophie, Heizen, Erin L., Ercan, Altan, Choi, Ickwon, Streeck, Hendrik, Nigrovic, Peter A., Bailey-Kellogg, Chris, Scanlan, Chris, Alter, Galit
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637034/
https://ncbi.nlm.nih.gov/pubmed/23563315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65708
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