Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

OBJECTIVE: To determine monoclonal antibody (mAb) features that predict fragment crystalizable (Fc)-mediated effector functions against HIV. DESIGN: Monoclonal antibodies, derived from Chinese hamster ovary cells or Epstein–Barr virus-immortalized mouse heteromyelomas, with specificity to key region...

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Vydáno v:AIDS
Hlavní autoři: Chung, Amy W., Crispin, Max, Pritchard, Laura, Robinson, Hannah, Gorny, Miroslaw K., Yu, Xiaojie, Bailey-Kellogg, Chris, Ackerman, Margaret E., Scanlan, Chris, Zolla-Pazner, Susan, Alter, Galit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429604/
https://ncbi.nlm.nih.gov/pubmed/25160934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000444
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