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A pharmacogenetic study of vorinostat glucuronidation
High interindividual pharmacokinetic variability was observed in phase 1 studies of vorinostat (suberoylanilide hydroxamic acid), an oral histone deacetylase inhibitor. Thus, we hypothesized that the variability can be explained by genetic variants of the uridine 5′-diphosphate-glucuronosyltransfera...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636562/ https://ncbi.nlm.nih.gov/pubmed/20729791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833e1b37 |
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