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Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology
INTRODUCTION: Recent discoveries of inherited glioma risk loci and acquired IDH mutations are providing new insights into glioma etiology. IDH mutations are common in lower grade gliomas and secondary glioblastomas and uncommon in primary glioblastomas. Because the inherited variant in 11q23 has bee...
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Prif Awduron: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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Oxford University Press
2013
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Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635511/ https://ncbi.nlm.nih.gov/pubmed/23361564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos324 |
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