Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology

INTRODUCTION: Recent discoveries of inherited glioma risk loci and acquired IDH mutations are providing new insights into glioma etiology. IDH mutations are common in lower grade gliomas and secondary glioblastomas and uncommon in primary glioblastomas. Because the inherited variant in 11q23 has bee...

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Main Authors: Rice, Terri, Zheng, Shichun, Decker, Paul A., Walsh, Kyle M., Bracci, Paige, Xiao, Yuanyuan, McCoy, Lucie S., Smirnov, Ivan, Patoka, Joseph S., Hansen, Helen M., Hsuang, George, Wiemels, Joe L., Tihan, Tarik, Pico, Alexander R., Prados, Michael D., Chang, Susan M., Berger, Mitchel S., Caron, Alissa, Fink, Stephanie, Kollmeyer, Thomas, Rynearson, Amanda, Voss, Jesse, Kosel, Matthew L., Fridley, Brooke L., Lachance, Daniel H., Eckel-Passow, Jeanette E., Sicotte, Hugues, O'Neill, Brian Patrick, Giannini, Caterina, Wiencke, John K., Jenkins, Robert B., Wrensch, Margaret R.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2013
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635511/
https://ncbi.nlm.nih.gov/pubmed/23361564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos324
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