Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology

INTRODUCTION: Recent discoveries of inherited glioma risk loci and acquired IDH mutations are providing new insights into glioma etiology. IDH mutations are common in lower grade gliomas and secondary glioblastomas and uncommon in primary glioblastomas. Because the inherited variant in 11q23 has bee...

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Detalhes bibliográficos
Main Authors: Rice, Terri, Zheng, Shichun, Decker, Paul A., Walsh, Kyle M., Bracci, Paige, Xiao, Yuanyuan, McCoy, Lucie S., Smirnov, Ivan, Patoka, Joseph S., Hansen, Helen M., Hsuang, George, Wiemels, Joe L., Tihan, Tarik, Pico, Alexander R., Prados, Michael D., Chang, Susan M., Berger, Mitchel S., Caron, Alissa, Fink, Stephanie, Kollmeyer, Thomas, Rynearson, Amanda, Voss, Jesse, Kosel, Matthew L., Fridley, Brooke L., Lachance, Daniel H., Eckel-Passow, Jeanette E., Sicotte, Hugues, O'Neill, Brian Patrick, Giannini, Caterina, Wiencke, John K., Jenkins, Robert B., Wrensch, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635511/
https://ncbi.nlm.nih.gov/pubmed/23361564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos324
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