Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis

BACKGROUND: Genome-wide association studies have implicated single nucleotide polymorphisms (SNPs) in 7 genes as glioma risk factors, including 2 (TERT, RTEL1) involved in telomerase structure/function. We examined associations of these 7 established glioma risk loci with age at diagnosis among pati...

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Detalhes bibliográficos
Main Authors: Walsh, Kyle M., Rice, Terri, Decker, Paul A., Kosel, Matthew L., Kollmeyer, Thomas, Hansen, Helen M., Zheng, Shichun, McCoy, Lucie S., Bracci, Paige M., Anderson, Erik, Hsuang, George, Wiemels, Joe L., Pico, Alexander R., Smirnov, Ivan, Molinaro, Annette M., Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael D., Lachance, Daniel H., Sicotte, Hugues, Eckel-Passow, Jeanette E., Wiencke, John K., Jenkins, Robert B., Wrensch, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714154/
https://ncbi.nlm.nih.gov/pubmed/23733245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not051
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