Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis

BACKGROUND: Genome-wide association studies have implicated single nucleotide polymorphisms (SNPs) in 7 genes as glioma risk factors, including 2 (TERT, RTEL1) involved in telomerase structure/function. We examined associations of these 7 established glioma risk loci with age at diagnosis among pati...

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Библиографические подробности
Главные авторы: Walsh, Kyle M., Rice, Terri, Decker, Paul A., Kosel, Matthew L., Kollmeyer, Thomas, Hansen, Helen M., Zheng, Shichun, McCoy, Lucie S., Bracci, Paige M., Anderson, Erik, Hsuang, George, Wiemels, Joe L., Pico, Alexander R., Smirnov, Ivan, Molinaro, Annette M., Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael D., Lachance, Daniel H., Sicotte, Hugues, Eckel-Passow, Jeanette E., Wiencke, John K., Jenkins, Robert B., Wrensch, Margaret R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714154/
https://ncbi.nlm.nih.gov/pubmed/23733245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not051
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