Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis

BACKGROUND: Genome-wide association studies have implicated single nucleotide polymorphisms (SNPs) in 7 genes as glioma risk factors, including 2 (TERT, RTEL1) involved in telomerase structure/function. We examined associations of these 7 established glioma risk loci with age at diagnosis among pati...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Walsh, Kyle M., Rice, Terri, Decker, Paul A., Kosel, Matthew L., Kollmeyer, Thomas, Hansen, Helen M., Zheng, Shichun, McCoy, Lucie S., Bracci, Paige M., Anderson, Erik, Hsuang, George, Wiemels, Joe L., Pico, Alexander R., Smirnov, Ivan, Molinaro, Annette M., Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael D., Lachance, Daniel H., Sicotte, Hugues, Eckel-Passow, Jeanette E., Wiencke, John K., Jenkins, Robert B., Wrensch, Margaret R.
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2013
الموضوعات:
Basic and Translational Investigations
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714154/
https://ncbi.nlm.nih.gov/pubmed/23733245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not051
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