Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

BACKGROUND: The prediction of clinical behavior, response to therapy, and outcome of infiltrative glioma is challenging. On the basis of previous studies of tumor biology, we defined five glioma molecular groups with the use of three alterations: mutations in the TERT promoter, mutations in IDH, and...

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Vydáno v:N Engl J Med
Hlavní autoři: Eckel-Passow, Jeanette E., Lachance, Daniel H., Molinaro, Annette M., Walsh, Kyle M., Decker, Paul A., Sicotte, Hugues, Pekmezci, Melike, Rice, Terri, Kosel, Matt L., Smirnov, Ivan V., Sarkar, Gobinda, Caron, Alissa A., Kollmeyer, Thomas M., Praska, Corinne E., Chada, Anisha R., Halder, Chandralekha, Hansen, Helen M., McCoy, Lucie S., Bracci, Paige M., Marshall, Roxanne, Zheng, Shichun, Reis, Gerald F., Pico, Alexander R., O’Neill, Brian P., Buckner, Jan C., Giannini, Caterina, Huse, Jason T., Perry, Arie, Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael D., Wiemels, Joseph, Wiencke, John K., Wrensch, Margaret R., Jenkins, Robert B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489704/
https://ncbi.nlm.nih.gov/pubmed/26061753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1407279
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