Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

BACKGROUND: The prediction of clinical behavior, response to therapy, and outcome of infiltrative glioma is challenging. On the basis of previous studies of tumor biology, we defined five glioma molecular groups with the use of three alterations: mutations in the TERT promoter, mutations in IDH, and...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Eckel-Passow, Jeanette E., Lachance, Daniel H., Molinaro, Annette M., Walsh, Kyle M., Decker, Paul A., Sicotte, Hugues, Pekmezci, Melike, Rice, Terri, Kosel, Matt L., Smirnov, Ivan V., Sarkar, Gobinda, Caron, Alissa A., Kollmeyer, Thomas M., Praska, Corinne E., Chada, Anisha R., Halder, Chandralekha, Hansen, Helen M., McCoy, Lucie S., Bracci, Paige M., Marshall, Roxanne, Zheng, Shichun, Reis, Gerald F., Pico, Alexander R., O’Neill, Brian P., Buckner, Jan C., Giannini, Caterina, Huse, Jason T., Perry, Arie, Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael D., Wiemels, Joseph, Wiencke, John K., Wrensch, Margaret R., Jenkins, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489704/
https://ncbi.nlm.nih.gov/pubmed/26061753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1407279
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