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Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
Normally post-mitotic neurons that aberrantly re-enter the cell cycle without dividing account for a substantial fraction of the neurons that die in Alzheimer's disease (AD). We now report that this ectopic cell cycle re-entry (CCR) requires soluble amyloid-β (Aβ) and tau, the respective buildi...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635465/ https://ncbi.nlm.nih.gov/pubmed/23345405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.1125880 |
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