In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

The Wnt target gene Lgr5 marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon(1), stomach(2) and hair follicles(3). A 3D culture system allows long-term clonal expansion of single Lgr5(+) stem cells into transplantable organoids that retain many c...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Huch, Meritxell, Dorrell, Craig, Boj, Sylvia F., van Es, Johan H., van de Wetering, Marc, Li, Vivian S.W., Hamer, Karien, Sasaki, Nobuo, Finegold, Milton J., Haft, Annelise, Grompe, Markus, Clevers, Hans
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634804/
https://ncbi.nlm.nih.gov/pubmed/23354049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11826
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars