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H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish exp...

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Detalhes bibliográficos
Main Authors: Neal, James T., Peterson, Tracy S., Kent, Michael L., Guillemin, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634662/
https://ncbi.nlm.nih.gov/pubmed/23471915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.011163
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