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Helicobacter pylori CagA Disrupts Epithelial Patterning by Activating Myosin Light Chain
Helicobacter pylori infection is a leading cause of ulcers and gastric cancer. We show that expression of the H. pylori virulence factor CagA in a model Drosophila melanogaster epithelium induces morphological disruptions including ectopic furrowing. We find that CagA alters the distribution and inc...
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Principais autores: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061873/ https://ncbi.nlm.nih.gov/pubmed/21445303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017856 |
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