Helicobacter pylori Activates Myosin Light-Chain Kinase To Disrupt Claudin-4 and Claudin-5 and Increase Epithelial Permeability

Helicobacter pylori is a spiral, gram-negative bacterium that specifically and persistently infects the human stomach. In some individuals, H. pylori-induced chronic gastritis may progress to gastroduodenal ulcers and gastric cancer. Currently, the host-microbe interactions that determine the clinic...

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Main Authors: Fedwick, Jason P., Lapointe, Tamia K., Meddings, Jonathan B., Sherman, Philip M., Buret, Andre G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307049/
https://ncbi.nlm.nih.gov/pubmed/16299274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7844-7852.2005
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