Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila

Helicobacter pylori strains containing the CagA protein are associated with high risk of gastric diseases including atrophic gastritis, peptic ulcers, and gastric cancer. CagA is injected into host cells via a Type IV secretion system where it activates growth factor-like signaling, disrupts cell-ce...

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Bibliografische gegevens
Hoofdauteurs: Reid, David W., Muyskens, Jonathan B., Neal, James T., Gaddini, Gino W., Cho, Lucy Y., Wandler, Anica M., Botham, Crystal M., Guillemin, Karen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2012
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417398/
https://ncbi.nlm.nih.gov/pubmed/22919616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2012.00024
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