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A Transgenic Drosophila Model Demonstrates That the Helicobacter pylori CagA Protein Functions as a Eukaryotic Gab Adaptor

Infection with the human gastric pathogen Helicobacter pylori is associated with a spectrum of diseases including gastritis, peptic ulcers, gastric adenocarcinoma, and gastric mucosa–associated lymphoid tissue lymphoma. The cytotoxin-associated gene A (CagA) protein of H. pylori, which is translocat...

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Detalhes bibliográficos
Main Authors: Botham, Crystal M., Wandler, Anica M., Guillemin, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364664/
https://ncbi.nlm.nih.gov/pubmed/18483552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000064
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