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Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line.

We have recently isolated overlapping recombinant cosmids that represent the equivalent of two complete dihydrofolate reductase (dhfr) amplicon types from the methotrexate-resistant Chinese hamster ovary (CHO) cell line CHOC 400. In the work described in this report, we used pulse-field gradient gel...

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Bibliografiska uppgifter
Huvudupphovsmän: Ma, C, Looney, J E, Leu, T H, Hamlin, J L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC363429/
https://ncbi.nlm.nih.gov/pubmed/2841578
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