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Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters

Interindividual variability in the expression of drug-metabolizing enzymes and transporters (DMETs) in human liver may contribute to interindividual differences in drug efficacy and adverse reactions. Published studies that analyzed variability in the expression of DMET genes were limited by sample...

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Autors principals: Yang, Lun, Price, Elvin T., Chang, Ching-Wei, Li, Yan, Huang, Ying, Guo, Li-Wu, Guo, Yongli, Kaput, Jim, Shi, Leming, Ning, Baitang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634068/
https://ncbi.nlm.nih.gov/pubmed/23637747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060368
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