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Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters

Variability in individual capacity for hepatic elimination of therapeutic drugs is well recognized and is associated with variable expression and activity of liver enzymes and transporters. Although genotyping offers some degree of stratification, there is often large variability within the same gen...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Pharmacol Ther
Hauptverfasser: Achour, Brahim, Al‐Majdoub, Zubida M., Grybos‐Gajniak, Agnieszka, Lea, Kristi, Kilford, Peter, Zhang, Mian, Knight, David, Barber, Jill, Schageman, Jeoffrey, Rostami‐Hodjegan, Amin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839483/
https://ncbi.nlm.nih.gov/pubmed/33141922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2102
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