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Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters

Variability in individual capacity for hepatic elimination of therapeutic drugs is well recognized and is associated with variable expression and activity of liver enzymes and transporters. Although genotyping offers some degree of stratification, there is often large variability within the same gen...

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Bibliografske podrobnosti
izdano v:Clin Pharmacol Ther
Main Authors: Achour, Brahim, Al‐Majdoub, Zubida M., Grybos‐Gajniak, Agnieszka, Lea, Kristi, Kilford, Peter, Zhang, Mian, Knight, David, Barber, Jill, Schageman, Jeoffrey, Rostami‐Hodjegan, Amin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839483/
https://ncbi.nlm.nih.gov/pubmed/33141922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2102
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