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Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human Liver

Human sex differences in the gene expression of drug metabolizing enzymes and transporters (DMETs) introduce differences in drug absorption, distribution, metabolism and excretion, possibly affecting drug efficacy and adverse reactions. However, existing studies aimed at identifying dimorphic expres...

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Détails bibliographiques
Publié dans:J Drug Metab Toxicol
Auteurs principaux: Yang, Lun, Li, Yan, Hong, Huixiao, Chang, Ching-Wei, Guo, Li-Wu, Lyn-Cook, Beverly, Shi, Leming, Ning, Baitang
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699760/
https://ncbi.nlm.nih.gov/pubmed/29177108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7609.1000119
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