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Multiscale modelling of drug transport and metabolism in liver spheroids
In early preclinical drug development, potential candidates are tested in the laboratory using isolated cells. These in vitro experiments traditionally involve cells cultured in a two-dimensional monolayer environment. However, cells cultured in three-dimensional spheroid systems have been shown to...
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| 出版年: | Interface Focus |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Royal Society
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061947/ https://ncbi.nlm.nih.gov/pubmed/32194929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2019.0041 |
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