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Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

In addition to primary human hepatocytes, hepatoma cell lines, and transfected nonhepatoma, hepatic cell lines have been used for pharmacological and toxicological studies. However, a systematic evaluation and a general report of the gene expression spectra of drug-metabolizing enzymes and transport...

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Detalhes bibliográficos
Main Authors: Guo, Lei, Dial, Stacey, Shi, Leming, Branham, William, Liu, Jie, Fang, Jia-Long, Green, Bridgett, Deng, Helen, Kaput, Jim, Ning, Baitang
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061558/
https://ncbi.nlm.nih.gov/pubmed/21149542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.035873
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