MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes

Cytochrome P450 2B6 (CYP2B6), mainly expressed in the liver and brain, is important for processing a number of widely used drugs. Variations in CYP2B6 expression are associated with decreased drug efficacy or adverse effects in some patients. Although CYP2B6 genetic variants are associated with its...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Pharmacol
Egile Nagusiak: Jin, Yaqiong, Yu, Dianke, Tolleson, William H., Knox, Bridgett, Wang, Yong, Chen, Si, Ren, Zhen, Deng, Helen, Guo, Yongli, Ning, Baitang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672627/
https://ncbi.nlm.nih.gov/pubmed/27311985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.06.007
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