The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p

Cytochrome P450 1A2 (CYP1A2) is one of the most abundant and important drug metabolizing enzymes in human liver. However, little is known about the post-transcriptional regulation of CYP1A2, especially the mechanisms involving microRNAs (miRNAs). This study applied a systematic approach to investiga...

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Pubblicato in:Biochem Pharmacol
Autori principali: Chen, Yinting, Zeng, Linjuan, Wang, Yong, Tolleson, William H., Knox, Bridgett, Chen, Si, Ren, Zhen, Guo, Lei, Mei, Nan, Qian, Feng, Huang, Kaihong, Liu, David, Tong, Weida, Yu, Dianke, Ning, Baitang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712447/
https://ncbi.nlm.nih.gov/pubmed/28822783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.08.012
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