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A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
Cytochrome P450 2E1 (CYP2E1) is an important drug metabolizing enzyme for processing numerous xenobiotics in the liver, including acetaminophen and ethanol. Previous studies have shown that microRNAs (miRNAs) can suppress CYP2E1 expression by binding to the 3′-untranslated region (3′-UTR) of its tra...
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| Publicado en: | Biochem Pharmacol |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703043/ https://ncbi.nlm.nih.gov/pubmed/28438567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.020 |
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