A systematic evaluation of microRNAs in regulating human hepatic CYP2E1

Cytochrome P450 2E1 (CYP2E1) is an important drug metabolizing enzyme for processing numerous xenobiotics in the liver, including acetaminophen and ethanol. Previous studies have shown that microRNAs (miRNAs) can suppress CYP2E1 expression by binding to the 3′-untranslated region (3′-UTR) of its tra...

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Publicado en:Biochem Pharmacol
Autores principales: Wang, Yong, Yu, Dianke, Tolleson, William H., Yu, Li-Rong, Green, Bridgett, Zeng, Linjuan, Chen, Yinting, Chen, Si, Ren, Zhen, Guo, Lei, Tong, Weida, Guan, Huaijin, Ning, Baitang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703043/
https://ncbi.nlm.nih.gov/pubmed/28438567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.020
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