A systematic evaluation of microRNAs in regulating human hepatic CYP2E1

Cytochrome P450 2E1 (CYP2E1) is an important drug metabolizing enzyme for processing numerous xenobiotics in the liver, including acetaminophen and ethanol. Previous studies have shown that microRNAs (miRNAs) can suppress CYP2E1 expression by binding to the 3′-untranslated region (3′-UTR) of its tra...

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Detaylı Bibliyografya
Yayımlandı:Biochem Pharmacol
Asıl Yazarlar: Wang, Yong, Yu, Dianke, Tolleson, William H., Yu, Li-Rong, Green, Bridgett, Zeng, Linjuan, Chen, Yinting, Chen, Si, Ren, Zhen, Guo, Lei, Tong, Weida, Guan, Huaijin, Ning, Baitang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703043/
https://ncbi.nlm.nih.gov/pubmed/28438567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.020
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