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Impact of Microbiome on Hepatic Metabolizing Enzymes and Transporters in Mice during Pregnancy

The microbiome and pregnancy are known to alter drug disposition, yet the interplay of the two physiologic factors on the expression and/or activity of drug metabolizing enzymes and transporters (DMETs) is unknown. This study investigated the effects of microbiome on host hepatic DMETs in mice durin...

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Detalles Bibliográficos
Publicado en:Drug Metab Dispos
Main Authors: Han, Lyrialle W., Wang, Lu, Shi, Yuanyuan, Dempsey, Joseph L., Pershutkina, Olesya V., Dutta, Moumita, Bammler, Theo K., Cui, Julia Y., Mao, Qingcheng
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434050/
https://ncbi.nlm.nih.gov/pubmed/32499338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.120.000039
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