Effect of Traumatic Brain Injury, Erythropoietin, and Anakinra on Hepatic Metabolizing Enzymes and Transporters in an Experimental Rat Model

In contrast to considerable data demonstrating a decrease in cytochrome P450 (CYP) activity in inflammation and infection, clinically, traumatic brain injury (TBI) results in an increase in CYP and UDP glucuronosyltransferase (UGT) activity. The objective of this study was to determine the effects o...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Anderson, Gail D., Peterson, Todd C., Vonder Haar, Cole, Farin, Fred M., Bammler, Theo K., MacDonald, James W., Kantor, Eric D., Hoane, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540723/
https://ncbi.nlm.nih.gov/pubmed/26068867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9792-y
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