Comparison of the Effect of Minocycline and Simvastatin on Functional Recovery and Gene Expression in a Rat Traumatic Brain Injury Model

The goal of this study was to compare the effects of minocycline and simvastatin on functional recovery and brain gene expression after a cortical contusion impact (CCI) injury. Dosage regimens were designed to provide serum concentrations in a rat model in the range obtained with clinically approve...

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Detalhes bibliográficos
Main Authors: Vonder Haar, Cole, Anderson, Gail D., Elmore, Brandy E., Moore, Lynn H., Wright, Amanda M., Kantor, Eric D., Farin, Fred M., Bammler, Theo K., MacDonald, James W., Hoane, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012634/
https://ncbi.nlm.nih.gov/pubmed/24308531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2013.3119
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