Á lódáil...

Development of modified siRNA molecules incorporating 5-fluoro-2′-deoxyuridine residues to enhance cytotoxicity

Therapeutic small interfering RNAs (siRNAs) are composed of chemically modified nucleotides, which enhance RNA stability and increase affinity in Watson–Crick base pairing. However, the precise fate of such modified nucleotides once the siRNA is degraded within the cell is unknown. Previously, we de...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Wu, Shao-yu, Chen, Tian-min, Gmeiner, William H., Chu, Edward, Schmitz, John C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2013
Ábhair:
RNA
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632118/
https://ncbi.nlm.nih.gov/pubmed/23449220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt120
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!