טוען...
Inhibition of MDR1 expression with altritol-modified siRNAs
Altritol-modified nucleic acids (ANAs) support RNA-like A-form structures when included in oligonucleotide duplexes. Thus altritol residues seem suitable as candidates for the chemical modification of siRNAs. Here we report that ANA-modified siRNAs targeting the MDR1 gene can exhibit improved effica...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851637/ https://ncbi.nlm.nih.gov/pubmed/17264131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1126 |
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