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Assignment of (1)H, (13)C and (15)N backbone resonances of Escherichia coli LpxC bound to L-161,240

The UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase LpxC catalyzes the committed reaction of lipid A biosynthesis, an essential pathway in Gram-negative bacteria. We report the backbone resonance assignments of the 34 kDa LpxC from Escherichia coli in complex with the antibiotic L-161...

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Autors principals: Barb, Adam W., Jiang, Ling, Raetz, Christian R. H., Zhou, Pei
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631426/
https://ncbi.nlm.nih.gov/pubmed/19941092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-009-9201-5
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