The calcineurin-NFAT pathway negatively regulates megakaryopoiesis

The calcium regulated calcineurin-nuclear factor of activated T cells (NFAT) pathway modulates the physiology of numerous cell types, including hematopoietic. Upon activation, calcineurin dephosphorylates NFAT family transcription factors, triggering their nuclear entry and activation or repression...

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Bibliographic Details
Main Authors: Zaslavsky, Alexander, Chou, Stella T., Schadler, Keri, Lieberman, Allyson, Pimkin, Maxim, Kim, Yeo Jung, Baek, Kwan-Hyuck, Aird, William C., Weiss, Mitchell J., Ryeom, Sandra
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
Subjects:
Platelets and Thrombopoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630833/
https://ncbi.nlm.nih.gov/pubmed/23446734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-421172
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