The Calcineurin-NFAT-Angiopoietin 2 signaling axis in lung endothelium is critical for the establishment of lung metastases

The pre-metastatic niche is a pre-determined site of metastases, awaiting the influx of tumor cells. However, regulation of the angiogenic switch at these sites has not been examined. Here we demonstrate that the calcineurin-NFAT pathway is activated specifically in lung endothelium prior to the det...

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Detalhes bibliográficos
Main Authors: Minami, Takashi, Jiang, Shuying, Schadler, Keri, Suehiro, Jun-ichi, Osawa, Tsuyoshi, Oike, Yuichi, Miura, Mai, Naito, Makoto, Kodama, Tatsuhiko, Ryeom, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763962/
https://ncbi.nlm.nih.gov/pubmed/23954784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.021
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