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Synergistic GABA-Enhancing Therapy against Seizures in a Mouse Model of Dravet Syndrome
Seizures remain uncontrolled in 30% of patients with epilepsy, even with concurrent use of multiple drugs, and uncontrolled seizures result in increased morbidity and mortality. An extreme example is Dravet syndrome (DS), an infantile-onset severe epilepsy caused by heterozygous loss of function mut...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3629796/ https://ncbi.nlm.nih.gov/pubmed/23424217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.203331 |
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