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DRAVET SYNDROME Insights into pathophysiology and therapy from a mouse model of Dravet syndrome

Mutations in voltage-gated sodium channels are associated with epilepsy syndromes with a wide range of severity. Complete loss of function in the Na(v)1.1 channel encoded by the SCN1A gene is associated with severe myoclonic epilepsy in infancy (SMEI), a devastating infantile-onset epilepsy with ata...

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Main Authors: Oakley, John C., Kalume, Franck, Catterall, William A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547637/
https://ncbi.nlm.nih.gov/pubmed/21463282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2011.03004.x
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