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Synergistic GABA-Enhancing Therapy against Seizures in a Mouse Model of Dravet Syndrome

Seizures remain uncontrolled in 30% of patients with epilepsy, even with concurrent use of multiple drugs, and uncontrolled seizures result in increased morbidity and mortality. An extreme example is Dravet syndrome (DS), an infantile-onset severe epilepsy caused by heterozygous loss of function mut...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Oakley, John C., Cho, Alvin R., Cheah, Christine S., Scheuer, Todd, Catterall, William A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Pharmacology and Experimental Therapeutics 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629796/
https://ncbi.nlm.nih.gov/pubmed/23424217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.203331
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