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Sudden unexpected death in a mouse model of Dravet syndrome

Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in intractable epilepsies, but physiological mechanisms that lead to SUDEP are unknown. Dravet syndrome (DS) is an infantile-onset intractable epilepsy caused by heterozygous loss-of-function mutations in the SCN1A gene, w...

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Autori principali: Kalume, Franck, Westenbroek, Ruth E., Cheah, Christine S., Yu, Frank H., Oakley, John C., Scheuer, Todd, Catterall, William A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613924/
https://ncbi.nlm.nih.gov/pubmed/23524966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66220
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