The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity

The Hippo (Hpo) pathway is a novel signaling pathway that controls organ size in Drosophila and mammals and is deregulated in a variety of human cancers. It consists of a set of kinases that, through a number of phosphorylation events, inactivate YAP, a transcriptional co-activator that controls cel...

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Autors principals: Michaloglou, Chrysiis, Lehmann, Waltraut, Martin, Typhaine, Delaunay, Clara, Hueber, Andreas, Barys, Louise, Niu, Honglin, Billy, Eric, Wartmann, Markus, Ito, Moriko, Wilson, Christopher J., Digan, Mary Ellen, Bauer, Andreas, Voshol, Hans, Christofori, Gerhard, Sellers, William R., Hofmann, Francesco, Schmelzle, Tobias
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628344/
https://ncbi.nlm.nih.gov/pubmed/23613971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061916
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