PTPN14 interacts with and negatively regulates the oncogenic function of YAP

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers where it promotes epithelial-to-mesenchyma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogene
Prif Awduron: Liu, X, Yang, N, Figel, SA, Wilson, KE, Morrison, CD, Gelman, IH, Zhang, J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402938/
https://ncbi.nlm.nih.gov/pubmed/22525271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.147
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