PTPN14 interacts with and negatively regulates the oncogenic function of YAP

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers where it promotes epithelial-to-mesenchyma...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Liu, X, Yang, N, Figel, SA, Wilson, KE, Morrison, CD, Gelman, IH, Zhang, J
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402938/
https://ncbi.nlm.nih.gov/pubmed/22525271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.147
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