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PTPN14 interacts with and negatively regulates the oncogenic function of YAP
The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. The pivotal effector of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers where it promotes epithelial-to-mesenchyma...
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| Publicado en: | Oncogene |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402938/ https://ncbi.nlm.nih.gov/pubmed/22525271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.147 |
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