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PTPN14 Forms a Complex with Kibra and LATS1 Proteins and Negatively Regulates the YAP Oncogenic Function

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. Pivotal effectors of this pathway are YAP/TAZ, transcriptional co-activators whose dysfunction contributes to epithelial-to-mesenchymal transition and mali...

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Detalhes bibliográficos
Main Authors: Wilson, Kayla E., Li, Ying-Wei, Yang, Nuo, Shen, He, Orillion, Ashley R., Zhang, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156080/
https://ncbi.nlm.nih.gov/pubmed/25023289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534701
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