PTPN14 Forms a Complex with Kibra and LATS1 Proteins and Negatively Regulates the YAP Oncogenic Function

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. Pivotal effectors of this pathway are YAP/TAZ, transcriptional co-activators whose dysfunction contributes to epithelial-to-mesenchymal transition and mali...

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Detaylı Bibliyografya
Asıl Yazarlar: Wilson, Kayla E., Li, Ying-Wei, Yang, Nuo, Shen, He, Orillion, Ashley R., Zhang, Jianmin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156080/
https://ncbi.nlm.nih.gov/pubmed/25023289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534701
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